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Methylphenidate for depression in hospice practice: A case series

The Harry R. Horvitz Center for Palliative Medicine (a World Health Organization Demonstration Project). The Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio

Declan Walsh, MSc, FACP

The Harry R. Horvitz Center for Palliative Medicine, The Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio

Kristine A. Nelson, MD

The Harry R. Horvitz Center for Palliative Medicine, The Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio

Susan LeGrand, MD

The Harry R. Horvitz Center for Palliative Medicine, Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio

Mellar Davis, MD

The Harry R. Horvitz Center for Palliative Medicine, The Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio

Psychostimulants such as methylphenidate have been used for depression in cancer patients. We report the successful use of methylphenidate to treat depression in 10 consecutive patients with advanced cancer. A rapid onset of effect was noted. Appetite, concentration, fatigue, and sedation also improved in some persons. No severe side effects were noted.

Key Words: cancer • depression • methylphenidate • psychostimulant • symptom management

American Journal of Hospice and Palliative Medicine®, Vol. 17, No. 6, 393-398 (2000)
DOI: 10.1177/104990910001700610


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