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American Journal of Hospice and Palliative Medicine®
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Acute pain in advanced cancer: An opioid dosing strategy and illustration

Mellar P. Davis, MD, FCCP

Harry R. Horvitz Center for Palliative Medicine, Cleveland Clinic Foundation, Cleveland, Ohio

Opioid dosing strategies for acute pain differ from strategies for chronic pain management. The basic principles of effective, safe dosing are rapid titration to the onset of analgesia followed by maintenance infusions based upon the titrated dose. This article presents guidelines and case histories for safe and effective dosing.

Key Words: pain management • opioid • palliative care • pharmacotherapy

American Journal of Hospice and Palliative Medicine®, Vol. 21, No. 1, 47-50 (2004)
DOI: 10.1177/104990910402100111
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