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American Journal of Hospice and Palliative Medicine®
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Dyspnea—A Bad Prognosis Symptom at the End of Life

Miguel Ángel Cuervo Pinna, MD

Regional Palliative Care Program of Extremadura, Palliative Care Team of Badajoz, Badajoz, Spain, 924252539{at}telefonica.net

Rafael Mota Vargas, MD

Regional Palliative Care Program of Extremadura, Palliative Care Team of Badajoz, Badajoz, Spain

María José Redondo Moralo, MD

Regional Palliative Care Program of Extremadura, Palliative Care Team of Badajoz, Badajoz, Spain

Miguel Ángel Sánchez Correas, MD

Regional Palliative Care Program of Extremadura, Palliative Care Team of Badajoz, Badajoz, Spain

Guillem Pera Blanco, PhD

Statistician Unitat de Suport a la Recerca Àmbit Barcelonès Nord i Maresme, Mataró, Barcelona, Spain

Purposes: Dyspnea as refractory symptom leading to sedation at the end of life and the place of death. Survival study in population with dyspnea.

Methods: Longitudinal study of terminally ill patients in a year (n = 195). We divided populations as (a) population with dyspnea: prevalent and incident dyspnea and (b) population without dyspnea. We used the statistical program Stata9 (Kaplan-Meier and Cox logistic regression models).

Results: The probability of being sedated was 5 times higher in population with dyspnea. Dying in hospital odds ratio was 2.13 in patients with dyspnea. The average survival time was 52 days in patients with dyspnea and 69 in non-dyspnea patients. The average survival was similar between both groups. Patients with incident dyspnea showed a higher average survival than those with prevalent dyspnea.

Conclusions: The connection between dyspnea and sedation was clearly shown. There were significant differences between prevalent dyspnea and incident dyspnea groups.

Key Words: dyspnea • place of death • sedation • average survival time

This version was published on April 1, 2009

American Journal of Hospice and Palliative Medicine®, Vol. 26, No. 2, 89-97 (2009)
DOI: 10.1177/1049909108327588
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